NOVOSERIES
HYDROXYPROPYL METHYL CELLULOSE (HPMC)
E CHEMISTRY 2910
| 1) | NOVOCOAT N-3 | (HPMC: 3 CPS) |
| 2) | NOVOCOAT N-5 | (HPMC: 5 CPS) |
| 3) | NOVOCOAT N-6 | (HPMC: 6 CPS) |
| 4) | NOVOCOAT N-15 | (HPMC: 15 CPS) |
| 5) | NOVOCOAT N-50 | (HPMC: 50 CPS) |
| 6) | NOVOCOAT NE -4M | (HPMC: 4000 CPS) |
| 7) | NOVOCOAT NE – 10M | (HPMC: 10000 CPS) |
| 8) | NOVOCOAT NE-15M – | (HPMC: 15000 CPS) |
| 9) | NOVOCOAT NE-100M | (HPMC: 100000 CPS) |
K CHEMISTRY 2208
1) NOVOCOAT NK-100LV | (HPMC: 100 CPS) | |
2) NOVOCOAT NK-4M | (HPMC: 4000 CPS) | |
3) NOVOCOAT NK-15M | (HPMC: 15000 CPS) | |
4) NOVOCOAT NK-100M | (HPMC: 100000 CPS) | |
5) NOVOCOAT NK-200M | (HPMC: 200000 CPS) |
POVIDONE/POLYVINYLPYRROLIDONE (PVP)
| 1) | NOVODONE 15 PF (PVP K-15) |
2) | NOVODONE 17 PF (PVP K-17) |
3) | NOVODONE 25 (PVP K-25) |
| 4) | NOVODONE 30 (PVP K-30) |
| 5) | NOVODONE 90 (PVP K-90) |
CROSPOVIDONE
| 1) | NOVODONE CR-L (Type – A) (Crospovidone – Particle Size: 50-110 micron) |
2) | NOVODONE CR-M (Type – B) (Crospovidone – Particle Size: 30-60 micron) |
3) | NOVODONE CR-S (Type – B) (Crospovidone – Particle Size: 10-20 micron) |
L-HPC
| 1) | NOVOCEL LH-11 (L-HPC 11) |
2) | NOVOCELLH-21 (L-HPC 21) |
| 3) | 3) NOVOCELLH-22 (L-HPC 22) |
CROSPOVIDONE
| 1) | NOVOSOL – ORAL |
2) | NOVOSOL – INJECTIBLE |
NOVOCOAT (HPMC)
Synonyms: Hydroxypropyl methylcellulose; HPMC; Hypromellosum.
Chemical Name: Cellulose Hydroxypropyl Methyl Ether
CAS No: 9004-65-3
Description: Novocoat is an odorless and tasteless, white to slightly off-white, fibrous or granular powder.
GRAS (Generally Recognized as Safe) listed Excipient
Application
Tablet – It is used for Sustained / Controlled / Modified / Immediate Release, Film Coating, Binding, Wet Granulation, Taste Masking.
Liquids – Solubilizer, Stabilizer, Taste Masking, Suspending Agent, Thickening Agent
Cream & Oinment – Thickening, Suspending & Steibilizing agent
Capsule – It is a vegetarian substitute of Gelatin for Capsule Shells.
Product – Novocoat N-3 (HPMC : 3 CPS), Novocoat N-5 (HPMC : 5 CPS), Novocoat N-6 (HPMC : 6 CPS), Novocoat N-15 (HPMC : 15 CPS)
Application – Wet Granulation, Tablet Coating, Vegetarian Substitute of Gelatin for Capsule Shells
Product – Novocoat – 50 (HPMC: 50 CPS)
Application – Table Coating
Product – Novocoat – 4M (HPMC: 4000 CPS)Novocoat – 10M (HPMC: 10000 CPS),Novocoat – 15M (HPMC: 15000 CPS), Novocoat – 100M (HPMC: 100000 CPS)
Application – Sustained/Controlled/Modified Immediate Release, Solubilizer, Stabilizer, Suspending Agent, Thickening Agent
Product – Novocoat NK – 100LV (HPMC: 100 CPS), Novocoat NK – 4M (HPMC: 4000 CPS), Novocoat NK – 15M (HPMC: 15000 CPS), Novocoat NK – 100M (HPMC: 100000 CPS), Novocoat NK – 200M (HPMC: 200000 CPS),
Application – Sustained/Controlled/Modified
NOVODONE (PVP)
Synonyms: Poly[1-(2-oxo-1-pyrrolidinyl) ethylene]; Polyvidone;Polyviny|pyrrolidone;Povidonum; Povipharm; PVP; 1-vinyl-2-pyrrolidinone polymer
Chemical Name: 1-Ethenyl-2-pyrrolidinone homopolymer
CAS No: 9003-39-8
Description: Novodone occurs as a fine, white to creamy-white colored, odorless or almost odorless, hygroscopic powder. It is a water-soluble polymer made from the monomer N- vinyl pyrrolidone:
GRAS (Generally Recognized as Safe) listed Excipient
Application
- NOVODONE is very good binder for aqueous and anhydrous system.
- It is used in wet granulation and direct compression.
- It is used as solubilizer in oral and parenteral formulations.
- It enhance dissolution of poorly soluble drugs.
- It is used as coating agent while coating of APl on sugar bead.
- It is used as a lubricant in some eye drops, Lyophilization agent, suspension stabilizer, complexing agent Apart of its pharma application it is also used in Glue stick, Cosmetics, Detergents, paint, ink etc.
|
PRODUCT NAME
|
K - VALUE
|
APPLICATION
|
|---|---|---|
|
NOVODONE 15 PF (PVP K 15)
|
12.75 - 17.25
|
Lyophilization agent, Suspension stabilizer, Complexing agent & Dissolution enhancer
|
|
NOVODONE 17 PF (PVP K 17)
|
15.3 - 18.36
|
Lyophilization agent, Suspension stabilizer, Complexing agent & Dissolution enhancer
|
|
NOVODONE 25 (PVP K 25)
|
22.5 - 27
|
Binder, Wet Granulation, Lyophilization agent, Complexing agent & Dissolution enhancer, solubilizer
|
|
NOVODONE 30 (PVP K 30)
|
27.0-32.4
|
Binder, Wet Granulation, Lyophilization agent, Complexing agent & Dissolution enhancer, solubilizer
|
|
NOVODONE 90 (PVP K 90)
|
81.0 - 97.2
|
Binder, Suspension stabilizer, Complexing agent & Dissolution enhancer, Thickner, Wet Granulation
|
Novodone CR (Crospovidone)
Synonyms: Crospovidonum; Crospopharm; crosslinked povidone; PVPP; 1-vinyl-2-pyrrolidinone Homopolymer;
Chemical Name: 1-Ethenyl-2-pyrrolidinone homopolymer
CAS No: 9003-39-8
Description: NOVODONE CR is a white to creamy-white, finely divided, free flowing, practically tasteless, odorless or nearly odorless, hygroscopic powder.
Application
- NOVODONE CR is mainly used as a super disintegrant in solid dosage forms.
- It not only gives faster disintegration but also enhance dissolution of drug.
- It can be used as solubility enhancer.
- NOVODONE CR Type-B provides smooth tablet surface.
- It provides good mouth feel for chewable tablets.
|
PRODUCT NAME
|
PARTICLE SIZE (p)
|
APPLICATION
|
|---|---|---|
|
NOVODONE CR-L (CROSPOVIDONE TYPE A)
|
50 -- 110
|
Super Disintegrant, Dissolution Enhancer
|
|
NOVODONE CR-M (CROSPOVIDONE TYPE B)
|
30 -- 60
|
Super Disintegrant, Dissolution Enhancer, Binder
|
|
NOVODONE CR-S (CROSPOVIDONE TYPE B)
|
10 -- 20
|
Super Disintegrant, Dissolution Enhancer, Dry Binder, Fine Particle Size Provide Smooth Tablet Surface & Improves Tablets Hardness
|
Novodone VA (Copovidone)
Synonyms: Acetic acid vinyl ester, polymer with 1-vinyl-2-pyrolidinone; copolymer of 1-vinyl-2-pyrrolidone and vinyl acetate in a ratio of 3: 2 by mass; copolyvidone; copovidonum, poly (1-viny pyrrolidone-co-vinyl acetate); polyviny|pyrrolidone-vinyl acetate copolymer; PVP/VA; PVP/VA copolymer.
Chemical Name: Acetic acid ethenyl ester, polymer with 1-ethenyl-2-pyrrolidinone
CAS No: 25086-89-9
Description: NOVODONE VA (Copovidone) is a white to yellowish-white amorphous powder. It is typically spray-dried with a relatively fine particle size. It has a slight odor and a faint taste.
GRAS (Generally Recognized as Safe) listed Excipient
Application
- NOVODONE VA is mainly used as tablet binder.
- It is also one of the excellent solubility enhancers.
- It is used as a part of the matrix material used in controlled-release formulations.
- It is often added to coating solutions as a film-forming agent.
- It is used as a binder for direct compression and wet granulation.
- It provides good adhesion, elasticity, and hardness, and also used as a moisture barrier.
|
USE
|
CONCENTRATION
|
|---|---|
|
Film-forming agent
|
0.5-5.0
|
|
Tablet binder, direct compression
|
2.0-5.0
|
|
Tablet binder, wet granulation
|
2.0-5.0
|
Novodone CR (Crospovidone)
Synonyms: Cellulose, 2-hydroxypropyl ether; 2-hydroxypropyl ether (low substituted) cellulose; hyprolose, low-substituted; oxypropylated cellulose
Chemical Name: Cellulose, 2-hydroxypropyl ether (low-substituted)
CAS No: 9003-64-2
Description: NOVOCEL-LH (Low-substituted hydroxypropyl cellulose) occurs as a white to yellowish white powder or granules. It is odorless or has a slight, characteristic odor, and it is tasteless.
Application
- NOVOCEL – LH is widely used in solid-dosage forms.
- It is primarily used as a binder and disintegrant tablet, as well as in granules in wet or dry granulations.
- It is used in the preparation of rapidly disintegrating tablets produced by DC methods.
- It also used in the powder layering process on spherical cores and to prepare pellets by extrusion/spheronization.
|
GRADE
|
APPLICATION
|
|---|---|
|
NOVOCEL LH - 11
|
As an anticapping agent and disintegrant for direct compression.
|
|
NOVOCEL LH - 21
|
Binder and disintegrant for tablets through the wet-granulation process
|
|
NOVOCEL LH - 22
|
Direct compression, Wet granulation & it has better disintegration capability
|
Novodone VA (Copovidone)
Synonyms: 2- Hydroxypropyl beta-cyclodextrin.
Chemical Name: ß-Cyclodextrin, 2-hydroxypropyl ether
CAS No: 94035-02-6
Description: Oral – White or almost white, amorphous or crystalline powder
Injectable – White powder, insipid, innocent
Application
- It can be used to provide excipient benefits in many oral dosage applications.
- It can improve the solubility of poorly soluble compounds and can be used for taste-masking of bitter or unpleasant active ingredients. It can also act as a stabilizer in these applications.
These products are for pharma oral dosage forms only, including swallowable tablets, chewable tablets, effervescent tablets, lozenges, hard capsules, soft capsules, orally dissolving films, blends, granules, pellets premix, medicated confectionary, syrups, suspensions, liquids, cream, paste and semi-solids.
Novosol Injectable grade are hydroxypropyl beta-cyclodextrin parenteral grade materials that are used as encapsulating agents for Rx injectables. These are modified betacyclodextrin for parenteral use. Modified beta-cyclodextrins used in parenteral preparations provide active substance stabilization improvement against light and oxidation as well as enhancement of solubilization of active pharmaceutical ingredients.